<p>Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity</p>
نویسندگان
چکیده
منابع مشابه
Synthesis and evaluation of biological properties of ferrocenyl-podophyllotoxin conjugates.
Three types, esters, amides and 1,2,3-triazoles, of ferrocenyl-podophyllotoxin conjugates were synthesised, and their anticancer activity was evaluated. We observed that the most potent ferrocenyl derivatives were esters. Esters 15, 16 and 17 acted in a similar way to podophyllotoxin, i.e. reduced the number of G1 phase cells and induced G2/M blockage, while esters 14 and 18 and amide 19 blocke...
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ژورنال
عنوان ژورنال: Drug Design, Development and Therapy
سال: 2019
ISSN: 1177-8881
DOI: 10.2147/dddt.s215895